Engineering New Markets and Strong Businesses
We invest in early-stage and breakthrough ventures that have the promise to create new market opportunities.
3-V Biosciences
3-V Biosciences is discovering and developing novel therapeutics for the treatment of infectious diseases. The company’s innovative strategy targets host pathways required for infection, providing major advantages over traditional pathogen-directed therapies. 3-V Biosciences is initially focused on treating respiratory viral illnesses, and its strategy is readily applicable to other types of infections.
Palo Alto, CA
3DV Systems
Breakthrough imaging technology captures the three dimensions of objects, enabling users to control personal space through intuitive body gestures.
Yokneam, Israel
3VR Security, Inc.
Has developed the world's first third generation video recorder.
San Francisco, CA
41st Parameter
Provides highly accurate, non-intrusive Internet fraud solutions for financial institutions and merchants.
Scottsdale, AZ
Aerohive Networks
Next-generation enterprise wireless LAN architecture.
Santa Clara, CA
AesThera
High technology aesthetics and advancements in the field of light-based aesthetic treatments.
Pleasanton, CA
Aggregate Knowledge
Performs item-to-item collaborative filtering in real time. Content Recommendation Services apply analytics across large datasets to derive and present personalized content recommendations for every visitor to your site.
San Mateo, CA.
Akimbo
Akimbo provides a complete solution for monetizing video over the Internet from content providers’ own websites.
San Mateo, CA
Altarock Energy Inc
A geothermal development company.
Sausalito, CA
Altra Biofuels
Developing and producing renewable fuels - ethanol and biodiesel.
Los Angeles, CA
Amyris Biotechnologies
Makes better molecules for the bio-fuels and bio-chemical industries using synthetic biology techniques.
Emeryville, CA
Anza Therapeutics
Anza Therapeutics is developing active immunotherapies for the treatment of infectious diseases and cancer. Anza’s therapeutic agents are based on its proprietary live-attenuated and Killed But Metabolically Active (KBMA) Listeria platforms which can be engineered to express antigens specific to the disease being treated.
Concord, CA
AOptix
AOptix Technologies is the leading edge developer of advanced iris recognition systems and free-space optical (FSO) laser communications solutions using Adaptive Optics, an imagery correction technology that compensates for motion and atmospheric disturbances as they happen.
Campbell, CA
Applied Minds
Explores and evaluates technology and teams, coaches and consults with entrepreneurs at a very early stage.
Glendale, CA
ArcSight
The leading vendor in security and compliance management.
Cupertino, CA
Arresto Biosciences
Arresto Biosciences is a biotech company that develops medicines to treat cancer and fibrotic diseases by targeting extracellular matrix proteins. Changes in the normal composition of the extracellular matrix of healthy tissues appear to play a role in the etiology of cancer and diseases with a fibrotic contribution such as liver cirrhosis, pulmonary fibrosis and scleroderma. The treatment of cancer and fibrotic diseases pose a huge unmet clinical need. Drugs that interact with components of the extracellular matrix could offer a treatment option for millions of patients worldwide.
Palo Alto, CA
Ausra
Ausra develops and deploys utility-scale solar technologies to serve global electricity needs in a dependable, market competitive, environmentally responsible manner.
Palo Alto, CA
AutoNavi
China's leading provider of digital map and location-based services for automotive and personal navigation systems, mobile and internet map applications and solutions. China Mobile's nationwide exclusive provider of geographic information system platform and digital map database.
Beijing, China
Autonomic Technologies, Inc.
Early stage start-up that develops medical devices to exploit the autonomic nervous system to alleviate pain and treat disease.
Redwood City, CA
Bit9, Inc.
Provides endpoint security software to help IT organizations increase the effectiveness of their endpoint security strategy while simplifying the effort it takes to manage those desktops.
Cambridge, MA.
Bloom Energy
Developing solid oxide regenerative fuel cells (SORFC) - renewable electrical energy generated from hydrogen and the oxygen in ambient air.
Sunnyvale, CA
Booyah
Booyah is a motivator for life and personal discovery.
Palo Alto, CA
Breathe Technologies
First provider of ultra lightweight and compact respiratory ventilator systems with the potential to transform hospital, homecare, and pandemic markets.
Fremont, CA
CardioDx
Developing molecular diagnostic products that serve cardiologists seeking answers to complex clinical questions in the areas of coronary artery disease, cardiac arrhythmias, and heart failure.
Palo Alto, CA
Cardium Therapeutics, Inc.
Therapeutic products and devices for cardiovascular, ischemic and related indications.
San Diego, CA
Celladon
Developing a gene therapy/delivery device combination (administered in a cardiac catheterization laboratory) for congestive heart failure.
La Jolla, CA
Chegg
Chegg.com is the number one textbook rental company. Chegg.com has saved millions of dollars for students at 4,000 plus campuses nationwide.
Santa Clara, CA
Codon Devices
Working to pioneer in the emerging field of synthetic biology.
Cambridge, MA
CoolIris
Revolutionizing the way we discover and interact with media by combining the best of desktop and web technologies.
Menlo Park, CA
Corthera
Corthera is a biopharmaceutical company committed to acquiring, developing and commercializing therapies for illnesses in the acute care setting.
San Mateo, CA
Corventis
Founded in 2005, Corventis, Inc. is developing wireless patient management solutions to address unmet clinical needs inherent in the treatment of high-risk patients across healthcare environments.
San Jose, CA
Crescendo Bioscience
Crescendo Bioscience is developing a broad range of quantitative, objective diagnostic tools to provide Rheumatologists with deeper clinical insights to more effectively manage patients with autoimmune and inflammatory diseases. The company is initially focused on rheumatoid arthritis.
South San Francisco, CA
Danoo
Danoo is a rapidly growing place-based digital media network that captures the attention of consumers in their favorite locations, as part of their daily ritual.
Dash Navigation
Connects people to the information that empowers them while in their cars.
Mountain View, CA
Devicescape (Formerly Instant 802 Networks Inc.)
A leading provider of advanced Wi-Fi software solutions that make mobile devices easy to set up, easy to use, and effortlessly connect to any Wi-Fi network.
San Bruno, CA
Digital Chocolate
Creating an entirely new category of mobile phone software for millions of consumers worldwide.
San Mateo, CA
EASIC
Developing a structured ASIC (shares characteristics of an FPGA and ASIC).
Santa Clara, CA
Elance
Elance is the leading site for online work, where businesses connect with independent professionals to get work done. On Elance, businesses find the experts they need plus the tools to manage online work from hiring to collaboration to making payment.
Mountain View, CA
Epizyme
Epizyme is a drug discovery and development company with the mission to translate today's science of epigenetics into important medicines of tomorrow.
Cambridge, MA
Fisker Automotive
Fisker Automotive is a green American premium sports car company with a mission to create a range of beautiful environmentally friendly cars that make environmental sense without compromise.
Five Prime Therapeutics
Developing innovative protein-based drugs for cancer, immune disease and diabetes discovered using breakthrough high throughput protein screening technologies.
San Francisco, CA
Fortify Software
Develops and sells solutions to detect security vulnerabilities in source code and to have them removed before the products are ever released.
Palo Alto, CA.
Friendster
An Internet-based social network in which consumers can find new friends, communicate with existing friends, and organize their social lives online.
Mountain View, CA
Glori Oil
State-of-the-art biotechnology solutions to improve and increase recovery from mature oil wells.
Houston, TX
GOGII
GOGII is a new social interaction and marketing platform.
Los Angeles, CA
GreatPoint Energy
Commercializing a proprietary catalytic process for converting coal (and other carbon-based feedstocks) into clean-burning, pipeline quality natural gas.
Cambridge, MA
Hara Software
Hara provides environmental and energy management solutions which help organizations grow and profit while optimizing natural resource consumption and reducing environmental impact. Hara gives customers auditable transparency and control of their organizational metabolism – the collective resources consumed and expended by an organization (energy, fossil fuels, water, waste, carbon and other resources) to improve their operational efficiency, maximize shareholder value and manage risks.
Menlo Park, CA
Hx Diagnostics
Rapid diagnostics for seasonal and emerging infectious diseases.
Emeryville, CA
iControl
iControl Networks is a technology and services innovator, providing mass-market, next-gen home management and monitoring solutions. Its user-friendly home solutions enable people to stay connected in real-time to what matters most—their family, property, home and business—anywhere, anytime over email, mobile, web and other access points.
Palo Alto, CA
Invuity
New technology in customized lighting and advanced visualization solutions for less invasive surgeries.
San Francisco, CA
IP Unity
Services platform and applications enable telecom service providers (wireless, wireline, and cable) to develop, manage and deploy revenue generating services.
Milpitas, CA
IronPlanet
Each year hundreds of millions of dollars worth of used construction equipment is sold through IronPlanet to businesses all over the world.
Pleasanton, CA
iZumi
iZumi is using the power of induced pluripotent stem cells (iPS) to transform drug discovery and regenerative medicine.
South San Francisco, CA
Ketera Technologies
A leading provider of spend analysis solutions with an "on demand" business model.
Santa Clara, CA
KnowNow Inc.
A leading provider of event-driven integration solutions.
Sunnyvale, CA
Kodiak Networks
Kodiak Networks is the leading provider of mobile solutions that are proven to help wireless operators increase revenue, promote community/group-based communications, and improve customer retention. Kodiak enables CDMA, GSM and UMTS carriers around the world to offer innovative mobile voice services via the comprehensive Kodiak Connected Portfolio.
Plano, TX
Kovio
Technology to enable printed electronics.
Sunnyvale, CA
Lehigh Technologies
Lehigh Technologies recycles tire rubber into fine, engineered powders with performance and cost advantages to rubber and specialty chemicals. Its powders can be used to extend the availability of rubber, improve existing product performance, create new specialty products and inspire innovation in sustainability.
Naples, FL
LifeLock, Inc.
The most advanced Identity Theft Protection solution available.
Lilliputian Systems
Miniature fuel cells for portable electronic devices and wireless appplications.
Wilmington, MA
Luca Technologies
Leveraging the ability of naturally occurring microorganisms to convert under-utilized domestic oil, organic-rich shale and coal resources to clean, renewable energy.
Golden, CO
M2Z Networks
Ad-supported wireless broadband Internet service.
Menlo Park, CA
Mascoma Corporation
Leading in the development of bio and process technology for cost-effective production of cellulosic ethanol, an inexpensive and source of renewable energy. Cambridge, MA
MetaMatrix
Provides solutions for federated data access and meta data management.
New York, NY
MetaRAM
Fabless semiconductor company focused on improving memory performance. The company's first product – MetaSDRAM™ – enables four times the amount of standard memory to be placed into existing systems without any modifications.
San Jose, CA
MetricStream
Enterprise Quality and Compliance Management Solutions.
Redwood Shores, CA.
Mevio
Personality-driven, broadband entertainment networks, each featuring top web celebrities bringing you the best clips and episodic series on the net.
San Francisco, CA
Miasole
Miasole is a low-cost, thin film CIGS solar company.
San Jose, CA
mKhoj
A performance driven mobile ad network that providers mobile publishers a way to monetize their traffic and gives advertisers with a targeted way to reach consumers while they surf the internet from their mobile phones.
Mumbai/ Bangalore, India
Mobilygen
Develops low-power H.264 codecs for mobile applications such as camcorders, solid-state digital cameras and cell phones.
Santa Clara, CA
Navigenics
Navigenics, Inc. specializes in personalized consumer health and wellness services, with the overall goal of improving health outcomes in individuals across the population. Navigenics educates and empowers consumers with knowledge of their genetic predispositions, and then motivates them to act on the information with support from their physician to prevent the onset of disease, achieve earlier diagnosis, appropriately manage disease or otherwise lessen its impact.
Redwood Shores, CA
New Vine Logistics
Proprietary fulfillment systems that enable fully compliant consumer-direct wine shipping across most of the United States.
Napa, CA
ng:moco, Inc.
ngmoco is focused on being the leading creator and publisher of breakthrough games for the iPhone.
San Francisco, CA
Nodality
Nodality is focused on patient-specific classification of disease.
San Francisco, CA
Oakley Networks
The leading provider of security appliances that monitor and prevent proprietary information leakage from commercial and government entities.
Salt Lake City, UT
Ocarina
Ocarina reduces data footprint with the world’s first file-aware storage optimization solution for online data.
San Jose, CA
One True Media, Inc.
Online service where visitors take digital media and express themselves in new and creative ways by eliminating the complexity inherent in video editing and making the entire process, from creation to output, fun and rewarding.
Redwood City, CA
OnFiber Communications, Inc.
Fiber optic local access networks.
Denver, CO
Ophthonix, Inc.
High-resolution lenses for vision correction.
Vista, CA
Optimedica
A global ophthalmic company dedicated to developing products that advance the practice of ophthalmology for the benefit of physicians and their patients.
Santa Clara, CA
Pacific Biosciences
Developing an ultra low-cost, ultra fast gene sequencing instrument and related reagents.
Menlo Park, CA
PayMate
Wireless transactions connecting banks, switches, merchants and customers using a simple, secure and seamless technology.
Mumbai, India
PeakStream
Building a breakthrough software platform for next-generation computing.
Redwood City, CA
Pelago, Inc.
Mobile community-based search and discovery application.
Seattle, WA
Pinger
Makers of good things for mobile phones.
San Jose, CA
Pixtronix, Inc.
Pixtronix develops breakthrough MEMS displays achieving ultra-low power consumption and exceptional video image quality, manufactured within existing LCD infrastructure.
Andover, MA
Presto
Connects friends and family by making it easy to share digital content. With Presto service and an HP Printing Mailbox, you can now send email and photos to people who do not have a computer or an internet connection.
Mountain View, CA.
Quorum Systems
Develops multi-mode radio tranceivers for cell phones.
San Diego, CA
RazorGator, Inc.
A leading provider of secondary tickets on the Internet for sports events, concert and theatre tickets.
Beverly Hills, CA
RecycleBank
RecycleBank works with municipalities and haulers to measure and reward residents for recycling. The more they recycle, the more RecycleBank points they accrue. These points are redeemable online and can be used with local and national merchants.
New York City, NY
RedBrick Health
RedBrick Health brings accountability to health care by linking health care financing and individual behavior. The company’s Health Earnings System allows employers to responsibly limit their financial health liability and for employees to earn all the rewards of better health through personalized health programs and advocacy services.
Minneapolis, MN
RGB Networks
Delivers next-generation video processing solutions that address the complexities of the emerging personalized video delivery environment.
Sunnyvale, CA
RPX Corporation
RPX Corporation is the first defensive patent aggregator. RPX acquires patent rights and provides them as a defensive patent aggregation for an annual membership fee to reduce technology companies’ patent risks and costs created by non-practicing entities (NPEs).
San Francisco, CA
Scintera Networks
Develops a high speed analog signal processor in CMOS focused on communications applications increasing spectral and power efficiency.
Sunnyvale, CA
Segway
Makers of the Segway Personal Transporter, the first two-wheeled, self-balancing, electric transportation device using patented dynamic stabilization technology.
Bedford, NH
Silecs, Inc.
Develops and manufactures advanced dielectric materials for semiconductor chips and flat panel displays, focused on enabling improved speed, power, density and image quality.
Mountain View, CA.
Silver Spring Networks, Inc.
Silver Spring Networks has created the technology, software and services to enable utilities to transmit and receive information from any point on the grid – also known as the Smart Grid. The Company’s patented technology enables its customers to enhance the reliability and quality of their services while at the same giving them the potential to better utilize their scarce power generating capacity, reduce carbon emissions and improve operating efficiency.
Redwood City, CA
Spatial Photonics, Inc.
Develops and manufactures innovative microdisplays for high definition, high brightness and high contrast projection displays.
Sunnyvale, CA
SpikeSource
Integrating open source middleware components for customers and providing service and support around these integrated stacks.
Redwood City, CA
Spinal Modulation
Developing a next generation Spinal Cord Stimulation (SCS) technology to treat chronic back and lower extremity pain.
Menlo Park, CA
SS8 Networks
Develops and sells telcom equipment for carriers that provides voicemail, voice-value add services, signaling and security solutions.
San Jose, CA
Stoke
Fixed mobile convergence technology.
Santa Clara, CA
Tellme Networks
Unites the Internet and telephone networks underneath an elegant speech user interface to provide the world’s largest Voice Application Network.
Mountain View, CA
Tethys Bioscience
Developing blood-based laboratory tests to determine an individual's risk for major chronic diseases (such as diabetes) and devastating health events (such as osteoporotic fractures), permitting physicians to focus effective preventative therapy on the millions of people at high risk who don't know they're at high risk.
Emeryville, CA
TherOx
Developing a new treatment to reduce infarct size in heart attack patients.
Irvine, CA
Tidal Software (formerly Intersperse)
Provides IT teams with the tools needed to monitor all the components and services across the enterprise.
Pasadena, CA
Trumba
Trumba Connect includes Web and email publishing tools that give you a better way to communicate events, activities and schedules.
Seattle, WA
Upromise
Harnessing the purchasing power of consumers in order to help them address some of the most important investments in life, starting with a college education.
Needham, MA
Veracyte
Veracyte is an early stage personalized medicine company focused on molecular diagnostics in thyroid cancer and lung cancer.
South San Francisco
Verdiem
Verdiem's SURVEYOR software provides measurable energy and cost savings through network-level control over PC and monitor power settings. SURVEYOR consistently reduces PC energy consumption by 30%-50%.
Seattle, WA
Vertica Systems
Vertica Systems has developed a very fast, highly scalable data warehouse database.
Billerica, MA
Virsa (acquired by SAP, April 2006)
Real time enterprise compliance solutions.
Visible Path
Provides companies with Relationship Capital Management (RCM) services to build, protect and extend corporate networks. Start building your private network today by registering at www.visiblepath.com
New York, NY
Vivaty
Vivaty is a web-based virtual world platform where users can personalize their own virtual scene and avatar and socialize with their friends.
Menlo Park, CA
WildBlue
Affordable satellite broadband service.
Englewood, CO
XDx, Inc.
Develops and markets molecular diagnostic tests for immune system measurement.
South San Francisco, CA
Xsigo
Xsigo Systems has developed the industry's first hardware-based solution that's purpose-built to virtualize I/O. Xsigo helps IT directors manage infrastructure quickly, precisely, and easily. I/O can be deployed when and where it's needed—in seconds, rather than days or weeks.
Sunnyvale, CA
Zagat
Strives to be the most trusted, useful, up-to-date guide to quality dining experiences focusing on discerning customers in the major business cities of the world.
New York, NY
Zazzle
The leading Internet marketplace for custom products.
Palo Alto, CA
Zettacore
Using unique molecules to replace the deep trench capacitors in a traditional DRAM cell.
Englewood, CO
Zynga
Zynga is leading the social gaming revolution by bringing its fun and contagious browser-based games to the mass market via online social networks.
San Francisco, CA

























